منابع مشابه
Tumor metastasis to bone
Establishment of skeletal metastasis involves bidirectional interactions between the tumor cell and the cellular elements in the bone microenvironment. A better understanding of the pathophysiology of bone metastasis will be critical in developing the means to prevent bone metastasis or inhibit its progression. The receptor activator of nuclear factor-kappaB (RANK)/RANK ligand pathway has emerg...
متن کاملMicrowave Tumor Ablation of Vertebral Bone Metastasis: A Case Report
Introduction: Thermal ablation by microwave (MWA) has proven efficacy in treatment of primary and metastatic cancers. Soft tissue tumors could be ablated completely using MWA. However, bony tissue metastasis particularly spinal vertebral metastasis ablation has not reported yet. Case presentation: A 50 year old male patient with primary diagnosed colon cancer undergone surgical resection of ...
متن کاملCD47 regulates bone mass and tumor metastasis to bone.
CD47, also called integrin-associated protein, plays a critical role in the innate immune response and is an atypical member of the immunoglobulin superfamily that interacts with and activates beta3 integrins. beta3 integrin(-/-) mice have defective platelet and osteoclast function and are protected from bone metastasis. The role of CD47 in skeletal homeostasis and bone metastasis has not been ...
متن کاملmicrowave tumor ablation of vertebral bone metastasis: a case report
introduction: thermal ablation by microwave (mwa) has proven efficacy in treatment of primary and metastatic cancers. soft tissue tumors could be ablated completely using mwa. however, bony tissue metastasis particularly spinal vertebral metastasis ablation has not reported yet. case presentation: a 50 year old male patient with primary diagnosed colon cancer undergone surgical resection of tum...
متن کاملOncostatin m promotes mammary tumor metastasis to bone and osteolytic bone degradation.
Oncostatin M (OSM) is an interleukin-6 (IL-6) family cytokine that has been implicated in a number of biological processes including inflammation, hematopoiesis, immune responses, development, and bone homeostasis. Recent evidence suggests that OSM may promote breast tumor invasion and metastasis. We investigated the role of OSM in the formation of bone metastases in vivo using the 4T1.2 mouse ...
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ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2007
ISSN: 1478-6354
DOI: 10.1186/ar2169